Pre-Emptive Intravenous Paracetamol and Lornoxicam in T hirdMolar Surgery

نویسندگان

  • Meltem Uyar
  • Esra Cagiran
  • Can Eyigor
  • Bahar Sezer
چکیده

Backgrounds: The objective of the present study was to compare the postoperative analgesic effects of pre-emptive intravenous (IV) paracetamol, lornoxicam and placebo following third molar surgery. Materials and Methods: This was a prospective, double-blind, randomized, placebo-controlled study where 50 patients had both of their identical impacted mandibular third molars impacted. Before the removal of the impacted third molar tooth on one side either of the two drug regimens (1g paracetamol or 8 mg lornoxicam) administered preemptively and 15 days later second surgical approach was performed but this time for comparison the other drug regimen (which was not chosen initially) was carried out as the preemptive agent; and all of the operations were performed by the same surgeon. Diclofenac sodium up to 75 mg daily was provided as rescue medication. The postoperative rescue analgesic consumption was recorded and pain scores were evaluated with a Verbal Rating Scale (VRS) at 15,30 min and 1,2, 4, 6, 12, 24 h postoperatively. Results: There was a significant difference in mean second hour VRS scores between paracetamol and lornoxicam group in favor of the lornoxicam (p<0.05). But, conversely, there was no statistically significant difference in the need of use and the consumption of rescue analgesic medication between two drug groups. Conclusion: Pre-emptive IV paracetamol and lornoxicam effectively decreased the pain scores as compared to placebo in third molar surgery.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Comparıson of different postoperative paın managements in patients submitted to transperitoneal laparoscopic renal and adrenal surgery.

PURPOSE We compared the effects of local levobupivacaine infiltration, intravenous paracetamol, intravenous lornoxicam treatments on postoperative analgesia in patients submitted to transperitoneal laparoscopic renal and adrenal surgery. MATERIALS AND METHODS Sixty adult patients 26 and 70 years who underwent laparoscopic renal and adrenal surgery were randomized into three groups with 20 pat...

متن کامل

Effect of intravenous paracetamol as pre-emptive compared to preventive analgesia in a pediatric dental setting: a prospective randomized study.

BACKGROUND Efficacy of pre-emptive analgesia compared to preventive regimen, managing postoperative pain is still controversial. AIM Evaluating the efficacy of intravenous (IV) paracetamol as pre-emptive analgesia compared to preventive post-treatment administration in pediatric dental setting. DESIGN In a prospective trial, 60 noncooperative children of ASA I, II aged 3-10 years who underw...

متن کامل

Postoperative analgesia in impacted third molar surgery: the role of preoperative diclofenac sodium, paracetamol and lornoxicam.

OBJECTIVE The aim of this study was to compare the postoperative analgesic effects of preoperative intravenous (i.v.) paracetamol, diclofenac sodium and lornoxicam (nonsteroidal anti-inflammatory drugs). SUBJECTS AND METHODS Sixty patients with impacted third molar who underwent surgical removal were randomly allocated into three groups: group P (n = 20), group D (n = 20) and group L (n = 20)...

متن کامل

Comparison of efficacy and tolerability of Tramadol with Lornoxicam as post operative pain management by administering pre-emptively in patients undergoing elective gynecological surgery under regional subarachnoid block anesthesia

Objective: The purpose of the present study was to determine the pre-emptive analgesic effects of Tramadol and Lornoxicam. Materials and Methods: Fifty women of ASA (American society of anaesthesiologists) class I and II, who were undergoing gynaecological surgeries under Regional subarachinoid block anaesthesia, were assigned in a randomized manner into two groups. Group T received a single IV...

متن کامل

Postoperative Analgesia in Impacted Third Molar Surgery: The Role of Preoperative Diclofenac Sodium, Paracetamol and Lornoxicam

Objective: The aim of this study was to compare the postoperative analgesic effects of preoperative intravenous (i.v.) paracetamol, diclofenac sodium and lornoxicam (nonsteroidal anti-inflammatory drugs). Subjects and Methods: Sixty patients with impacted third molar who underwent surgical removal were randomly allocated into three groups: group P (n = 20), group D (n = 20) and group L (n = 20)...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2013